Explain how the transcriptome helps us to better understand the differences between cells from different types of tissues that are specialized for different functions.

Please write one paragraph for each topic. Do not include the instructions in your response.

This week is all about our DNA and gene expression. The complete set of all DNA in a cell is called the genome. The complete set of all the mRNA in a cell is called the transcriptome. Read the following article about the transcriptome found at: https://www.genome.gov/13014330/transcriptome-fact-sheet/, then address the following:

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• Explain how the transcriptome helps us to better understand the differences between cells from different types of tissues that are specialized for different functions.

• What do you think is the most interesting or significant thing about the transcriptome?

In multicellular organisms, most cells that are created by mitosis are integrated into the structure of the organism. This week’s lesson looks at what happens to cells that don’t integrate properly, that are not needed, or that fail certain quality-control checkpoints in the cell cycle. Watch the Khan Academy video about apoptosis found at: https://www.khanacademy.org/science/biology/cellular-molecular-biology/stem-cells-and-cancer/v/apoptosis then address the following two issues:
• Describe at least two ways that apoptosis helps animals.

• What aspect of apoptosis do you find most interesting or significant? Explain.

This week you are exploring how emerging DNA technologies impact our society. View the NBC News story about CRISPR found at: https://www.nbcnews.com/dateline/video/life-changer-965215299885, then, address the following questions:
• What applications of CRISPR look particularly promising for improving human well-being? Justify your response.

• Discuss the ethical issues you believe have arisen or are likely to arise with the deployment of CRISPR.

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