Mrs is an 80 year old woman awaiting discharge following a left hemiarthroplasty.

Mrs is an 80 year old woman awaiting discharge following a left hemiarthroplasty.

Mrs is an 80 year old woman awaiting discharge following a left hemiarthroplasty. The nurse observes that she is shivering and complaining of feeling cold but, on examination, has a temp of 38oC. A midstream specimen of urine reveals high levels of leucocytes and nitrites in her urine.
a) with reference to the underlying pathophysiology explain why she feels cold despite the fact her temp is elevated? 35%
b)what factors have contributed to the risk of her developing a urinary tract infection (UTI) 20%
Mrs is prescribed Trimethoprim 200 mg, BD
c) with reference to the pharmacodynamics and pharmacokinetics discuss the use of Trimethoprim to treat her’s UTI including any risk factors. 35%

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